Drug details:
Molecular formula: C₂₀H₁₄N₂O₃

Standard name: (4E)-4-[(1-acetylindol-3-yl)methylidene]-2-phenyl-1,3-oxazol-5-one

Synonyms:

(4E)-4-[(1-acetylindol-3-yl)methylidene]-2-phenyl-1,3-oxazol-5-one (4E)-4-[(1-acetyl-3-indolyl)methylidene]-2-phenyl-5-oxazolone (4E)-4-[(1-acetylindol-3-yl)methylene]-2-phenyl-2-oxazolin-5-one (4E)-4-[(1-ethanoylindol-3-yl)methylidene]-2-phenyl-1,3-oxazol-5-one (4E)-4-[(1-acetyl-1H-indol-3-yl)methylidene]-2-phenyl-1,3-oxazol-5(4H)-one (4E)-4-[(1-ACETYL-1H-INDOL-3-YL)METHYLIDENE]-2-PHENYL-4,5-DIHYDRO-1,3-OXAZOL-5-ONE

Curated SMILES: CC(=O)N1C=C(C2=CC=CC=C21)/C=C/3\C(=O)OC(=N3)C4=CC=CC=C4

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Motility
Target: Not determined
Drug effect: Inhibits sliding motility and then results in a decrease in bacterial virulence.
Max phase: Preclinical (in vitro)
Publication:
Ouertatani-Sakouhi H, et al., 2017. Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model. PLoS One 12(7):e0181121.