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Luteolin

Drug details:
Molecular formula: C15H10O6

Classification: Flavones; Flavonoids; Phenylpropanoids and polyketides; Organic compounds;
Synonyms:  3',4',5,7-Tetrahydroxyflavone
Digitoflavone
Luteolol
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
Flacitran
Luteoline
Salifazide
Weld Lake
Yama kariyasu
......

Chemical structure:
Depiction based on curated SMILES HO HO OH OH O O

Evidence for compound's anti-virulence activity:

Aeromonas
Related VF: Aerolysin
Target: AerA/Act
Drug effect: Inhibits aerolysin oligomerization.
Max phase: Preclinical (in vitro)
Publication:
Dong J, et al., 2021. Luteolin decreases the pathogenicity of Aeromonas hydrophila via inhibiting the activity of aerolysin. Virulence 12(1):165-176.








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