Drug details:
Molecular formula: C₆H₈O₄

Standard name: 3,5-dihydroxy-6-methyl-2,3-dihydropyran-4-one

Synonyms:

2,3-Dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl- 3,5-Dihydroxy-6-methyl-2H-pyran-4(3H)-one 3,5-dihydroxy-6-methyl-2,3-dihydropyran-4-one 3,5-Dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one 2,3-Dihydro-3,5-dihydroxy-6-methyl-4(H)-pyran-4-one 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone dnd-omi 70 nmol/L 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyranone ......

Curated SMILES: CC1=C(C(=O)C(CO1)O)O

Evidence for compound's anti-virulence activity:

Aeromonas
Related VF: Aerolysin
Target: AerA/Act
Drug effect: Inhibits aerolysin oligomerization.
Max phase: Preclinical (in vitro)
Publication:
Arumugam M, et al., 2023. Evaluating Biofilm Inhibitory Potential in Fish Pathogen, Aeromonas hydrophila by Agricultural Waste Extracts and Assessment of Aerolysin Inhibitors Using In Silico Approach. Antibiotics (Basel) 12(5):891.