Drug details:
Molecular formula: C₁₃H₁₅N₅

Standard name: 4,6-dimethyl-N-[(Z)-1-pyridin-2-ylethylideneamino]pyrimidin-2-amine

Curated SMILES: CC1=CC(=NC(=N1)N/N=C(/C)\C2=CC=CC=N2)C

Evidence for compound's anti-virulence activity:

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: Preclinical (in vivo)
Publication:
Paschos A, et al., 2011. An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation. Infect Immun 79(3):1033-43.