Drug details:
Molecular formula: C₁₄H₁₀N₂O₂

Standard name: 3-phenyl-2H-phthalazine-1,4-dione

Synonyms:

3-phenyl-2H-phthalazine-1,4-dione 4-Hydroxy-2-phenylphthalazin-1(2H)-one 2,3-Dihydro-2-p CCG-25354 3-phenyl-2H-phthalazine-1,4-quinone 2-Phenylphthalazine-1,4(2H,3H)-dione 3,4-Dihydro-2-phenyl-1,4-phthalazinedione 2-Phenyl-2,3-dihydro-1,4-phthalazinedione # 1,2,3,4-Tetrahydro-1,4-dioxo-2-phenylphthalazine 2-phenyl-1,2,3,4-tetrahydrophthalazine-1,4-dione

Curated SMILES: O=C1NN(C2=CC=CC=C2)C(=O)C2=C1C=CC=C2

Evidence for compound's anti-virulence activity:

Shigella
Related VF: VirF
Target: VirF
Drug effect: Inhibits transcriptional activator.
Max phase: Preclinical (in vitro)
Publication:
Hurt JK, et al., 2010. High-throughput screening of the virulence regulator VirF: a novel antibacterial target for shigellosis. J Biomol Screen 15(4):379-87.