Drug details:
Molecular formula: C₂₀H₁₅N₃O₂

Standard name: 3-(4-methoxyphenyl)-2-pyridin-3-ylquinazolin-4-one

Curated SMILES: COC1=CC=C(C=C1)N2C(=NC3=CC=CC=C3C2=O)C4=CN=CC=C4

Evidence for compound's anti-virulence activity:

Klebsiella
Related VF: Aerobactin
Target: IucA
Drug effect: Inhibits aerobactin synthetase IucA activity.
Max phase: Preclinical (in vitro)
Publication:
Bailey DC, et al., 2018. Development of a High-Throughput Biochemical Assay to Screen for Inhibitors of Aerobactin Synthetase IucA. SLAS Discov 23(10):1070-1082.