Drug details:
Molecular formula: C₁₈H₁₉Cl₂N₃O₅S₂

Standard name: 5-chloro-N-[(4-chlorophenyl)methyl]-N-(1,1-dioxothiolan-3-yl)-2-ethylsulfonylpyrimidine-4-carboxamide

Synonym:

5-chloro-N-(4-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-2-(ethylsulfonyl)pyrimidine-4-carboxamide

Curated SMILES: CCS(=O)(=O)C1=NC=C(C(=N1)C(=O)N(CC2=CC=C(C=C2)Cl)C3CCS(=O)(=O)C3)Cl

Evidence for compound's anti-virulence activity:

Vibrio
Related VFcategory: Stress survival
Target: Not determined
Drug effect: Inhibits σE stress response pathway of Vibrio cholerae that is required for full virulence of the organism.
Max phase: Preclinical (in vitro)
Publication:
Stanbery L, et al., 2017. Assay development and high-throughput screening for small molecule inhibitors of a Vibrio cholerae stress response pathway. Drug Des Devel Ther 11:2777-2785.