Drug details:
C22H17N3O3
Diphenylethers; Benzene and substituted derivatives; Benzenoids; Organic compounds;
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Evidence for compound's anti-virulence activity:
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Biofilm
MvfR
Inhibits MvfR-regulated virulence functions.
Preclinical (in vitro)
Singh VK, et al., 2022. Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy. Nat Commun 13(1):5103.
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