Drug details:
Molecular formula: C₁₉H₁₈N₂O₄

Standard name: (4E)-4-[(2,3-dihydro-1,4-benzodioxin-6-ylamino)methylidene]-2-(4-methylphenyl)-1,3-oxazolidin-5-one

Curated SMILES: CC1=CC=C(C2=N/C(=C/NC3=CC=C4OCCOC4=C3)C(=O)O2)C=C1

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Blocks translocation of effectors into host cells.
Max phase: Preclinical (in vitro)
Publication:
Harmon DE, et al., 2010. Identification and characterization of small-molecule inhibitors of Yop translocation in Yersinia pseudotuberculosis. Antimicrob Agents Chemother 54(8):3241-54.

Yersinia
Related VF: TTSS (Type III secretion system)
Target: Yops
Drug effect: Inhibits translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publication:
Harmon DE, et al., 2010. Identification and characterization of small-molecule inhibitors of Yop translocation in Yersinia pseudotuberculosis. Antimicrob Agents Chemother 54(8):3241-54.