Drug details:
Molecular formula: C₇H₈N₂O₄

Standard name: 3,4,5-trihydroxybenzohydrazide

Synonyms:

3,4,5-Trihydroxybenzohydrazide gallic hydrazide gallic acid hydrazone 3,4,5-Trihydroxybenzohydrazide # 3,4,5-tris(oxidanyl)benzohydrazide

Curated SMILES: C1=C(C=C(C(=C1O)O)O)C(=O)NN

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VFcategory: Biofilm
Target: DGC
Drug effect: Inhibits of diguanylate cyclase (DGC) enzymes that synthesize c-di-GMP that is essential for biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Sambanthamoorthy K, et al., 2015. Modulating Acinetobacter baumannii biofilm development with molecules containing 3,4,5-trimethoxy-N,N',N'-trimethylbenzohydrazide moiety. Bioorg Med Chem Lett 25(10):2238-42.