Drug details:
Molecular formula: C₂₀H₁₂O₇

Standard name: 3',4',5',6'-tetrahydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one

Synonyms:

Alizarin violet Pyrogallolphthalein 3',4',5',6'-Tetrahydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one Pyrogallol phthalein 4,5-Dihydroxyfluorescein Callein Alizarine violet 3',4',5',6'-Tetrahydroxyfluoran Fluorescein, 4',5'-dihydroxy- ......

Curated SMILES: O=C1OC2(C3=CC=CC=C13)C1=CC=C(O)C(O)=C1OC1=C2C=CC(O)=C1O

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VFcategory: Others; Biofilm
Target: PPK
Drug effect: Attenuates many virulence factors including biofilm formation, surface associated motility by inhibiting polyphosphate kinase (PPK) activity.
Max phase: Preclinical (in vitro)
Publication:
Roberge N, et al., 2021. Broad-Spectrum Inhibitor of Bacterial Polyphosphate Homeostasis Attenuates Virulence Factors and Helps Reveal Novel Physiology of Klebsiella pneumoniae and Acinetobacter baumannii. Front Microbiol 12:764733.

Klebsiella
Related VFcategory: Others; Biofilm
Target: PPK
Drug effect: Attenuates many virulence factors including biofilm formation by inhibiting polyphosphate kinase (PPK) activity.
Max phase: Preclinical (in vitro)
Publication:
Roberge N, et al., 2021. Broad-Spectrum Inhibitor of Bacterial Polyphosphate Homeostasis Attenuates Virulence Factors and Helps Reveal Novel Physiology of Klebsiella pneumoniae and Acinetobacter baumannii. Front Microbiol 12:764733.