Escherichia
Related VF: TTSS (Type III secretion system)
Target: NleB1
Drug effect: Inhibits the activity of Escherichia coli NleB1.
Max phase: Preclinical (in vitro)
Publication: El Qaidi S, et al., 2018. High-Throughput Screening for Bacterial Glycosyltransferase Inhibitors. Front Cell Infect Microbiol 8:435.
Salmonella
Related VF: TTSS (SPI-2 encode)
Target: SseK1/SseK2
Drug effect: Inhibits SseK1/SseK2 Arg glycosyltransferase activity.
Max phase: Preclinical (in vitro)
Publication: El Qaidi S, et al., 2018. High-Throughput Screening for Bacterial Glycosyltransferase Inhibitors. Front Cell Infect Microbiol 8:435.