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Compound category: Phenylpropanoids and polyketides
(total 104 related compounds in database, current show from 81 to 90)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(E)-N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)-3-[3-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]prop-2-enamide Depiction based on curated SMILES S S O O CH 3 S H 3 C N HN O O N Shigella TTSS (Type III secretion system) Preclinical (in vitro) Case HB, et al. 2018. Biochemistry
Oroxylin A Depiction based on curated SMILES OH O CH 3 O HO O Staphylococcus Others Preclinical (in vitro) Jiang X, et al. 2023. J Appl Microbiol
Astilbin Depiction based on curated SMILES O OH OH HO HO OH HO HO H H H H H H 3 C O O H H O Streptococcus Others; Adherence; Biofilm Preclinical (in vitro) Wang J, et al. 2019. Molecules
Rutin Depiction based on curated SMILES O O HO OH OH OH OH OH HO HO HO HO H H H H H O O CH 3 H H H H H O O Streptococcus Others Preclinical (in vitro) Yang WY, et al. 2016. J Microbiol Biotechnol
Theaflavine Depiction based on curated SMILES OH O HO OH HO OH O OH HO HO O OH Streptococcus Biofilm Preclinical (in vitro) Kong J, et al. 2021. AMB Express
4-({[2-(3-iodophenyl)-1,3-benzoxazol-5-yl]imino}methyl)-2-methoxyphenyl 2,4-dichlorobenzoate Depiction based on curated SMILES O I O N Cl Cl N O CH 3 O Vibrio VAS T6SS Preclinical (in vitro) Sun K, et al. 2014. Antimicrob Agents Chemother
3-[1-[3-(1,3-benzothiazol-2-ylamino)-3-oxopropyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES O HO HO N N N H N S N O O Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[3-(9H-fluoren-9-ylamino)-3-oxopropyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES N N O N H N O OH O HO Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[3-(benzhydrylamino)-3-oxopropyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES N N O NH N O OH O HO Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[3-(benzylamino)-3-oxopropyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES N O HO HO N NH N O O Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
   


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