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Compound category: Phenylpropanoids and polyketides
(total 104 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(-)-Hopeaphenol Depiction based on curated SMILES HO O OH HO HO OH OH O HO HO OH OH Pseudomonas
Yersinia
TTSS (Type III secretion system)
TTSS (Type III secretion system)
Preclinical (in vivo)
Preclinical (in vivo)
Zetterström CE, et al. 2013. PLoS One
Quercitrin Depiction based on curated SMILES O OH HO OH OH OH OH OH H H H H H 3 C H O O O Salmonella
Staphylococcus
Effector delivery system
Adherence; Others
Preclinical (in vivo)
Preclinical (in vitro)
Li Q, et al. 2023. Molecules
Liu B, et al. 2015. Molecules
Kaempferol Depiction based on curated SMILES OH OH O O HO HO Listeria
Streptococcus
LLO (Listeriolysin O)
Pneumolysin
Preclinical (in vivo)
Preclinical (in vivo)
Wang T, et al. 2022. Microbiol Spectr
Xu L, et al. 2023. Microbes Infect
Acacetin Depiction based on curated SMILES O HO OH CH 3 O O Listeria
Streptococcus
LLO (Listeriolysin O)
Pneumolysin
Preclinical (in vivo)
Preclinical (in vivo)
Li S, et al. 2022. Foodborne Pathog Dis
Li S, et al. 2020. J Pharm Pharmacol
Ginkgetin Depiction based on curated SMILES HO O OH O O OH O O CH 3 O CH 3 OH Streptococcus Suilysin Preclinical (in vivo) Li G, et al. 2019. J Appl Microbiol
Corilagin Depiction based on curated SMILES O O O OH OH OH OH OH OH OH O O O HO HO OH OH O Streptococcus Pneumolysin Preclinical (in vivo) Sheng Q, et al. 2022. Molecules
2',4'-Dihydroxychalcone Depiction based on curated SMILES HO OH O Vibrio HlyU Preclinical (in vivo) Imdad S, et al. 2018. Molecules
N-(4-oxo-4H-thieno[3,4-c]chromen-3-yl)-3-phenylprop-2-ynamide Depiction based on curated SMILES S O O O N H Vibrio HlyU Preclinical (in vivo) Lee ZW, et al. 2019. Sci Rep
3-Nitrocinnamic acid Depiction based on curated SMILES + N O _ O O HO Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
Baicalein Depiction based on curated SMILES HO HO OH O O Listeria LLO (Listeriolysin O) Preclinical (in vivo) Wang J, et al. 2015. Sci Rep; Lu G, et al. 2019. J Cell Mol Med
   


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