|
| Virstatin |
|
Acinetobacter
Vibrio |
TFP (Type IV pili)
TCP (Toxin-coregulated pilus) |
Preclinical (in vitro)
Preclinical (in vivo) |
Nait Chabane Y, et al. 2014. BMC Microbiol
Hung DT, et al. 2005. Science |
|
| 5-Fluorouracil |
|
Staphylococcus
Vibrio |
Biofilm
Biofilm |
Preclinical (in vivo)
Preclinical (in vivo) |
Sedlmayer F, et al. 2021. Nucleic Acids Res
|
|
| Fursultiamin |
|
Vibrio |
HlyU |
Preclinical (in vivo) |
Imdad S, et al. 2018. Front Cell Infect Microbiol |
|
Compound 8
(internal name in literature) |
|
Vibrio |
TCP (Toxin-coregulated pilus) |
Preclinical (in vivo) |
Woodbrey AK, et al. 2018. Biochemistry |
|
| 5-amino-1-(5-chloro-2-methylphenyl)-4-(6-methyl-1H-benzimidazol-2-yl)-1,2-dihydro-3H-pyrrol-3-one |
|
Vibrio |
Stress survival |
Preclinical (in vitro) |
Stanbery L, et al. 2017. Drug Des Devel Ther |
|
| 3-(4-fluorophenyl)-2-methyl-5-{[(4-methylphenyl)sulfanyl]methyl}pyrazolo[1,5-a]pyrimidin-7(4H)-one |
|
Vibrio |
Stress survival |
Preclinical (in vitro) |
Stanbery L, et al. 2017. Drug Des Devel Ther |
|
| 3-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)propan-1-ol |
|
Vibrio |
Post-translational modification |
Preclinical (in vitro) |
Wang G, et al. 2022. ChemMedChem |
|
| 4,4'-[(5,5-Dioxidodibenzo[b,d]thiene-2,8-diyl)bis(oxy)]diphthalonitrile |
|
Vibrio |
VAS T6SS |
Preclinical (in vitro) |
Sun K, et al. 2014. Antimicrob Agents Chemother |
|
| Isonaamine A |
|
Vibrio |
Biofilm |
Preclinical (in vitro) |
Mai T, et al. 2015. Lett Appl Microbiol |
|
| Isonaamine D |
|
Vibrio |
Biofilm |
Preclinical (in vitro) |
Mai T, et al. 2015. Lett Appl Microbiol |
|
| | | |
