Home
 Search
 Category
 Compounds
 Status
 Download
 Contacts
 Resources


Compound category: Organoheterocyclic compounds
(total 15 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(5E)-5-({4-[(2,4-DICHLOROPHENYL)METHOXY]-3-ETHOXYPHENYL}METHYLIDENE)-1-(3,5-DIMETHYLPHENYL)-1,3-DIAZINANE-2,4,6-TRIONE Depiction based on curated SMILES H 3 C CH 3 O O Cl Cl O CH 3 O NH O N Clostridium
Streptococcus		 theta-toxin/PFO (Perfringolysin O)
Pneumolysin		 Preclinical (in vitro)
Preclinical (in vitro)		 Aziz UBA, et al. 2024. Nat Commun
(5E)-5-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-1-(3,5-dimethylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione Depiction based on curated SMILES CH 3 O N H O Cl Cl O CH 3 O N Clostridium
Streptococcus		 theta-toxin/PFO (Perfringolysin O)
Pneumolysin		 Preclinical (in vitro)
Preclinical (in vitro)		 Aziz UBA, et al. 2024. Nat Commun
[6,7-bis(chloranyl)-3-phosphono-quinoxalin-2-yl]phosphonic acid Depiction based on curated SMILES OH OH O P OH OH O P N N Cl Cl Bacillus
Clostridium		 Collagenase
Collagenase		 Preclinical (in vitro)
Preclinical (in vitro)		 Alhayek A, et al. 2022. J Med Chem
11-(3-Methoxy-phenyl)-5,11-dihydro-10-thia-5-aza-dibenzo[a,g]azulen-12-one Depiction based on curated SMILES NH O H 3 C S O Clostridium TcdB (Toxin B) Preclinical (in vitro) Farrow MA, et al. 2020. ACS Chem Biol
3-(4-nitrophenyl)furo[3,2-g]chromen-7-one Depiction based on curated SMILES O _ O O + N O O Clostridium BoNT (Botulinum neurotoxin) Preclinical (in vitro) Patel KB, et al. 2018. Appl Environ Microbiol
3-cyclohexyl-1-[4-(2-methoxyphenyl)piperazin-1-yl]propan-1-one Depiction based on curated SMILES O CH 3 N N O Clostridium TcdB (Toxin B) Preclinical (in vitro) Farrow MA, et al. 2020. ACS Chem Biol
Amlodipine Depiction based on curated SMILES CH 3 H 3 C Cl CH 3 O O HN H 2 N O O O Clostridium TcdB (Toxin B) Preclinical (in vitro) Farrow MA, et al. 2020. ACS Chem Biol
5-acetyl-3-amino-4-(4-bromophenyl)-6-methyl-4,7-dihydrothieno[2,3-b]pyridine-2-carboxamide Depiction based on curated SMILES Br S O H 2 N CH 3 NH 2 HN CH 3 O Clostridium TcdB (Toxin B) Preclinical (in vitro) Farrow MA, et al. 2020. ACS Chem Biol
5-{3-[(2,4-difluorophenoxy)methyl]-4-methoxybenzylidene}-2,4,6(1H,3H,5H)-pyrimidinetrione Depiction based on curated SMILES O F F O O N H CH 3 HN O O Clostridium
Streptococcus		 theta-toxin/PFO (Perfringolysin O)
Pneumolysin		 Preclinical (in vitro)
Preclinical (in vitro)		 Aziz UBA, et al. 2024. Nat Commun
5-{4-[(2,4-dichlorobenzyl)oxy]-3-ethoxybenzylidene}pyrimidine-2,4,6(1H,3H,5H)-trione Depiction based on curated SMILES Cl Cl O O NH O H 3 C HN O O Clostridium
Streptococcus		 theta-toxin/PFO (Perfringolysin O)
Pneumolysin		 Preclinical (in vitro)
Preclinical (in vitro)		 Aziz UBA, et al. 2024. Nat Commun
   


NOTE: for more interactive and statistic charts, please visit the JavaScript-rich interface of VFDB.



Page  1  2 



Back to top
2004-2025 NIPB, CAMS&PUMC