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Compound category: Chalcones and dihydrochalcones
(total 7 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
2',4'-Dihydroxychalcone Depiction based on curated SMILES HO OH O Vibrio HlyU Preclinical (in vivo) Imdad S, et al. 2018. Molecules
Phloretin Depiction based on curated SMILES HO OH OH O HO Acinetobacter
Listeria
BfmRS
LLO (Listeriolysin O)
Preclinical (in vitro)
Preclinical (in vivo)
Raorane CJ, et al. 2019. Front Microbiol
Wang J, et al. 2017. Front Cell Infect Microbiol
2'-Hydroxychalcone Depiction based on curated SMILES OH O Clostridium Collagenase Preclinical (in vitro) Nitulescu G, et al. 2022. Life (Basel)
Licochalcone A Depiction based on curated SMILES OH H 3 C O HO O CH 3 H 2 C CH 3 Enterococcus Biofilm Preclinical (in vitro) Marcoux E, et al. 2020. Arch Oral Biol
(E)-1-(2-hydroxyphenyl)-3-(1-naphthyl)prop-2-en-1-one Depiction based on curated SMILES OH O Mycobacterium Exoenzyme Preclinical (in vitro) Chiaradia LD, et al. 2008. Bioorg Med Chem Lett; Mascarello A, et al. 2010. Bioorg Med Chem
1-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-en-1-one Depiction based on curated SMILES H 3 C O CH 3 O O Mycobacterium Exoenzyme Preclinical (in vitro) Chiaradia LD, et al. 2008. Bioorg Med Chem Lett; Mascarello A, et al. 2010. Bioorg Med Chem
1-(3''-methoxy-4''-hydroxyphenyl)-3-(2-naphthyl)-2-propen-1-one Depiction based on curated SMILES OH CH 3 O O Mycobacterium Exoenzyme Preclinical (in vitro) Chiaradia LD, et al. 2008. Bioorg Med Chem Lett; Mascarello A, et al. 2010. Bioorg Med Chem
   
   
   
   
   
   
   


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